Flucan (fluconazole tablets) is used to treat serious fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis. The tablets work by stopping the growth and reproduction of fungi. Fluconazole is usually taken orally, with or without food, and is available in various strengths. It is important to complete the full course of medication as directed by a healthcare professional, even if symptoms improve before the end of the course.